HIV is a systemic infection caused by Human Immunodeficiency Virus. A few days or weeks after infection, there may be the symptoms of an acute viral infection—fever, muscle pain, and malaise. An HIV infection may result in nonspecific skin lesions of the mucous membranes, such as rash, herpes, recurrent infectious impetigo, folliculitis, tinea versicolor, or oral hairy leukoplakia.